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Published: August 10, 2023

Restylane or Botox: Deciphering the Best Solution for Facial Aging

What do you think about when people mention aesthetic plastic surgery? Hopefully, the first thing that comes to your mind is a simple injectable treatment in a cosmetic clinic because this way of skin rejuvenation is proven to be one of the most popular options in this field nowadays. That’s why we would like to dedicate today’s article to brands with the same aesthetic goal yet differ in composition and working principles. As you may have guessed, we are talking about Botox and Restylane injections for a youthful appearance.

Follow this article to learn more about how people can benefit from these injections, their primary dissimilarities, and other essentials. We believe understanding the differences is important for the overall treatment’s success, so what are you waiting for? Let’s dive into this exciting topic!


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Restylane vs. Botox – the Basics

Before comparing Botox and fillers from the Restylane family, mentioning the essentials is good, as it can help understand both treatments at their core. Even though the final goals of both products are the same – to reduce facial wrinkles and improve one’s appearance, the ways they do this are entirely different. So, without further ado, let’s begin!

When to Use Restylane?

Restylane is a hyaluronic acid injectable used for numerous purposes; whether you need to enhance facial features, augment lips, or get rid of deep lines and creases, – this brand can do it all. Cross-linked HA of non-animal origin promises a safe procedure with immediate results, and the chances of severe adverse reactions are minimal if you talk about injectables like Restylane. Another benefit of this product is its natural ability to boost skin hydration, improving skin elasticity, tone, and texture. One year is the average longevity, but it still varies based on personal factors that must be discussed with a specialist before the injection session.

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When to Use Botox?

Botox belongs to injectable neurotoxins used for cosmetic purposes, as well as treating some muscle spasm-related medical conditions. It’s one of the best options for preventing aging signs, and even though restoring volume and filling in wrinkles is not Botox’s primary task, it can still eliminate wrinkles caused by facial movement (also known as dynamic lines). By blocking nerve signals in target muscles, this solution provides skin improvement that lasts four to six months and can be easily supported with the help of timely scheduled injection sessions. Talk to a specialist to determine the best plan for one’s aesthetic goals.

The Main Differences

While the previous paragraph was dedicated to the basics of Botox and Restylane, this one is about the differences between these popular brands. Knowing those is essential to decide which one to use to reach maximum improvement; who knows, maybe you’d better combine them for a more striking result?

Active Substance

Botox and hyaluronic acid dermal fillers work differently in their core. HA injectables are typically used to fill in skin depressions, restore lost volume, and make facial more even and smoother; botulinum toxins, on the other hand, are muscle relaxants, meaning their primary task is to stop muscle contraction by blocking nerve endings for some time. So, what does it say about Restylane and Botox?

  • Botox treatment includes botulinum toxin type A, and it works well for dynamic lines prevention;
  • Restylane soft tissue fillers work well for already present aging signs, such as nasolabial folds, marionette lines, smile lines, and others. It’s excellent when it comes to volume restoration in hollow facial zones, as well as gentle lip augmentation.

Botox or restylane injections

Target Areas and Injectables’ Longevity

Both Restylane and Botox cosmetic injectable treatments are typically used for pre-defined facial areas to provide an excellent result and natural-looking improvement. Just like that, we have a list of recommendations here to help you understand the basics.

Botox is the best solution for dynamic wrinkles, which include:

  • Crow’s feet in the outer eye corners;
  • Glabellar lines, or vertical “eleven” lines between the eyebrows;
  • Horizontal forehead wrinkles.

As for Restylane hyaluronic acid filler, it shows the best results when used for:

  • Volume restoration in cheeks;
  • Shape correction in the chin and nose;
  • Lip enhancement and contouring (also works well for asymmetry correction);
  • Wrinkles reduction (marionette lines, nasolabial folds, etc.).

*Restylane filler injections are also great for skin hydration improvement, as hyaluronic acid is famous for its hydrating abilities. 

Speaking about the longevity of both products, the results are long-lasting for non-surgical treatments. After targeting facial muscles, Botox injections provide four to six months of noticeable improvement; Restylane injectable cosmetic treatments last a little longer, as the body needs time to dissolve it (from eight to sixteen months based on the filler formulation, aesthetic request, a patient’s age, and some other factors).

*Some specialists combine Botox and Restylane for a more prolonged effect. First, dermal filler is used to fill in already existing imperfections; next, botulinum toxin injection is introduced to prevent the occurrence of aging signs for up to half a year. 

More About the Price

The treatment’s cost is another vital factor people consider before deciding which product to choose for their aesthetic needs. If you want to buy Botox, you should expect the price to be around $430 per box; as for the average cost of Restylane, the prices start from $170 per package. However, it depends on the filler type, as Restylane has a wide range of injectables that vary in density, HA concentration, and some other essential factors.

As for the treatment cost in a clinic, it may change based on its location, a doctor’s price list, as well as patient’s cosmetic requests. This factor should be discussed during the consultation before the injection session to calculate the numbers for an individual and tell them how much they would need per procedure.


One of the essential steps before the injection session is to ensure the procedure is safe for an individual and won’t cause any complications once finished. Here are some of the conditions that may be considered contraindications for the treatment:

  • Known bleeding disorders;
  • Allergies related to any components of the injectable;
  • Skin damage or irritation in the target spots;
  • Pregnancy or breastfeeding;
  • Current intake of medications incompatible with the composition of Botox or Restylane (sometimes, it’s impossible to postpone or pause meds therapy, so it’s better to look for alternative cosmetic procedures or discuss the treatment plan with a medical professional to come up with the safest option).

Another vital requirement is that a person should be over the age of 21 for the process to be non-problematic and successful. Some treatments are recommended to be used after 25, but that should be discussed with a specialist according to one’s needs and current skin statement.

How Is the Procedure Performed?

Restylane and Botox treatments have a similar procedure protocol, although their working principles differ. Before the injection session, a patient’s aesthetic requests must be discussed to define the target spots and injectable dose needed to deal with the problem; the number of treatments is also calculated there. Afterward, the process may begin.

A person should come to the clinic barefaced (of course, products used in skincare routines like SPF can still be applied). Before the product’s administration, target areas are carefully cleaned so all the external premises and contaminants are removed; the region should be sterile for a safe experience. In case a person has a low pain tolerance, they can request a topical numbing cream used as an anesthetic; with its help, it’s easier to eliminate any discomfort caused by the needle puncture or solution injection. Sometimes a doctor may massage the face after the appointment to spread out the product under the skin evenly and ensure there are no irritations once the procedure is finished. It’s also better to discuss the aftercare plan with a specialist to highlight all the risks and assure a patient knows when to contact their doctor.

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What About the Side Effects?

A Botox injection and Restylane dermal filler can cause adverse reactions, both minor and more severe. And while the first ones are pretty easy to handle (we are talking about local irritations and increased skin sensitivity), serious side effects must be reported to a specialist immediately to prevent them from worsening. A person has to tell their doctor if they notice such reactions as:

  • Severe allergies (includes trouble breathing, swollen tongue, closed throat, and others);
  • Irregular heartbeat or chest pain;
  • Loss of consciousness, sudden body temperature decrease;
  • Fever, dizziness, and other flu-like symptoms;
  • Painful sensations in the injection spots.

Informing a specialist on time is vital to a person’s safety, so explain it to them and instruct them to pay close attention to unusual side effects for at least 24 hours after the administration session.

To Sum Up: Botox vs. Restylane

If we talk about injectables like Restylane and Botox, it’s crucial to understand all the dissimilarities to select the best brand and fulfill all patients’ cosmetic needs. Due to different active substances (hyaluronic acid and botulinum toxin type A) and working principles (volume restoration and muscle contractions pausing), these products cannot be considered the same, even though the goal for both is to provide an excellent facial rejuvenation effect. To choose the right brand for the treatment, a person must go to the doctor’s office, describe their aesthetic requests, and come up with the most optimal solution. And the best thing is, it doesn’t matter which brand will be picked – they are both safe, effective and provide natural-looking skin improvement. So, what are you waiting for? It’s time to set an appointment in a clinic today!