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Published: October 9, 2023

Xeomin vs Botox: Decoding the Differences for Wrinkle Reduction

Botulinum toxin type A is probably one of the best solutions when it comes to muscle spasm treatments; widely in both medical and aesthetic spheres, these products deserve excellent reputation among medical professionals around the world. However, as there are plenty of options containing botulinum, sometimes people get confused, as it’s unclear what the main differences are between them. Today, we want to decode the main dissimilarities between the two top brands often compared in the “botulinum toxin winners” discussions – Xeomin and Botox.

How are these two different, and which one to choose? Are they irreplaceable? Is it safe to buy them online? This article will cover all the questions, so join us on this exciting journey to understand all the specifics about Botox and Xeomin. Let’s begin!

Before we start, we would like to remind you that OGOMED is a perfect Botox wholesale supplier (USA). We offer you a wide range of products at quite advantageous prices, so check out available brands and stock up on everything you may need for your work. We are looking forward to our successful cooperation!

A Few Words About the Brands

Before starting our extensive comparison, we believe discussing the specifics of Botox and Xeomin is essential. Even though they are quite similar, they are still unique, so it’s vital to understand them to pick the best treatment option for patients with various requests.

More About Xeomin Injections

Xeomin is a botulinum toxin type A-based injectable by the global pharmaceutical company Merz. This product is a perfect option for cosmetic treatment for the prevention and reduction of aging signs; just like that, specialists use it to deal with dynamic lines that appear early on the facial surface.

On top of that, Xeomin is also suitable for muscle spasm-related medical conditions, like chronic migraines, overactive bladder syndrome, and other similar issues. A doctor must inspect a patient and make the correct conclusion about their current health situation to create a treatment plan that includes Xeomin. Dosage and procedure frequency are also calculated during the consultation.

If the session follows all safety rules, the results should develop within a week and continue for approximately three to six months. They can be easily supported with regularly performed touch-up treatments (once again, the frequency should be discussed with a medical professional).

All the Essential About Botox

Botox treatments also belong to botulinum toxin type A procedures. The manufacturer of this product is Allergan, also known for other popular brands in the cosmetic beauty sphere: Juvederm, Coolsculpting, and numerous others.

Just like Xeomin, Botox is used to treat facial lines, prevent dynamic wrinkles, and help patients maintain younger-looking appearances. It’s also widely used for some medical conditions, such as abnormal muscle contractions, urinary incontinence, excessive sweating, etc.

For Botox to work properly, it must be administered directly into the muscle to ensure the solution reaches the nerve endings of the treatment site. Up to two weeks are required to see the full effect, and the results gradually fade after six months. As with most rejuvenating procedures, Botox requires maintenance treatments approximately every six months to preserve the results and provide people with the appearance they have always dreamt of.

Attractive woman at plastic surgery with syringe in her face

Botox vs. Xeomin: The Big Comparison

Now that all the basics are highlighted let’s get to the comparison. Even though similar, Xeomin and Botox have certain dissimilarities that must be highlighted to pick the most suitable brand for the treatment. Let’s discuss them!

Manufacturer and Composition

Xeomin and Botox injections have different manufacturers. While the first one is the creation of Merz, the second one is produced by Allergan. Still, both companies have excellent reputations and have been present on the market long enough to deserve the trust of their customers.

To buy Xeomin online or order Botox on this website, you must be a board-certified medical professional. Using these products is only allowed if a specialist has a proper education and a perfect knowledge of the human body anatomy.

As for the composition, Botox and Xeomin contain botulinum toxin type A as the active ingredient. However, generic names for them vary: Xeomin’s is incobotulinumtoxinA, and Botox’s is onabotulinumtoxinA. What does it mean?

In simple words, Xeomin is a “naked” injectable that contains pure botulinum without any additives; it also means there are fewer chances that the organism will develop antibodies, so adverse reactions are rarer with Xeomin. Botox, on the other hand, also includes proteins to make the solution stronger.


The cost difference between the two brands is insignificant: 100 units of Xeomin (it equals one vial) cost around $350, while the price of the same amount of Botox is approximately $400. Here, we indicate prices online, which may vary slightly from supplier to supplier. Be ready for that, and don’t choose the cheapest option, as cheap doesn’t always mean safe. The quality of the product is essential and must be your main priority to provide a positive experience to your patients. Look for a reliable supplier like OGOMED and buy Xeomin and Botox advantageously in a few quick clicks!

Dosage and Working Principle

Xeomin and Botox treatment can only be performed after the consultation in a doctor’s office. This is the only way to calculate the best dosage for the injection session and reach the desired goal in the end. Normally, a specialist uses one vial per injection session, varying sizes between 50 and 100 units.

Regarding the working principle, it’s practically identical for both brands:

  • After the solution is introduced into the muscle, it needs time to reach the nerve endings and block their contractions. This way, muscles become numb, and the occurrence of dynamic wrinkles is paused;
  • Temporal relaxation reduces spasms and contractions, which solves most problems Botox and Xeomin are used for.

The Initial Goal

Even though Botox and Xeomin have similar cosmetic and medical purposes, there is one vital difference that must be considered before the injection session.

Xeomin is a perfect solution for treating facial lines and wrinkles; it perfectly deals with crow’s feet, forehead lines, and other issues. Using it for migraines, overactive bladder syndrome, and other similar matters is considered off-label. Despite that, many specialists still use it for those goals. Botox, on the other hand, has its FDA approval and can be safely picked for both medical and cosmetic procedures.

Both Xeomin and Botox are mainly associated with dynamic wrinkles, meaning they are practically useless when it comes to severe lines. For deeper creases, we recommend using hyaluronic acid dermal fillers; they are the most effective when it comes to volume restoration.


Regarding side effects, those are practically identical for Botox and Xeomin. Another treatment option should be picked for the procedure if a patient matches at least one of the following contraindications:

  • A person is allergic to botulinum toxin or any other component of the solution;
  • A person lives with severe conditions (including such issues as untreated epilepsy, poor blood clotting, diabetes mellitus, and others);
  • A person must take prescribed medications which are incompatible with Botox or Xeomin;
  • A person has damaged or inflamed skin in the injection spot;
  • A person has recently gone through cosmetic treatments that damage skin, like chemical peelings;
  • A person is younger than 18 years old (in rare situations, these products can be prescribed for kids who suffer from uncontrollable muscle contractions);
  • A person is pregnant or nursing.

All these issues must be discussed in advance during the consultation in the doctor’s office, as ignoring them may be dangerous and can potentially lead to health complications. Thus, be careful and always mention all the essentials in advance.

Adverse Reactions

Botox and Xeomin injectable treatments are considered to be among the safest ones known in the cosmetic beauty sphere. The concentration of botulinum is not too high to actually hurt a person – just enough to pause muscle contractions and prevent dynamic wrinkles.

  • Still, even though these products are FDA-approved, some patients experience side effects, as it’s a natural reaction of the body to the unknown solution. Generally, people experience the following symptoms after the session:
  • Local skin irritation in the administration spot, including redness, swelling, etc.;
  • High sensitivity in the target area;
  • Short-lasting migraines.

Patients shouldn’t be worried about previously mentioned adverse rations, as they tend to disappear within a few hours after the appointment. Individuals with sensitive skin may need one to two days to recover fully. However, a specialist must warn people about more severe adverse reactions. Even though rare, those can be dangerous if not treated on time, so pay close attention to:

  • Signs of severe allergies (swollen throat, tongue, etc.);
  • Trouble breathing;
  • Painful sensation in the administration spot;
  • Facial numbness;
  • Loss of consciousness;
  • And so on.

If a specialist is informed about the problem on time, it’s easier to take the situation under control. Thus, please be careful and pay attention to the symptoms during the recovery stage.


An important thing to remember about Xeomin and Botox treatments is that their results are not permanent. That means the procedure should be performed again after some time to support the effect. The average longevity of both brands is six months, so specialists recommend having a maintenance session every four months to ensure the nerve endings won’t regain their activity.

In Conclusion: Xeomin Injections vs. Botox

Botox and Xeomin are effective and safe products, both containing botulinum toxin type A. That means they belong to muscle relaxants and are typically used to deal with muscle spam-related conditions, like migraines, excessive sweating, overactive bladder, and other problems of a similar nature.

The main difference between these products is the composition: while Xeomin contains pure botulinum toxin, Botox has added proteins that let it last longer. On the other hand, adverse reactions are rarer for Xeomin, so both injectables can be considered beneficial. To pick the right solution, visiting a doctor’s office and discussing all the needs with a specialist is essential. Hopefully, now you understand the nature of both brands better. Thank you for visiting the blog!