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Published: November 23, 2023

Evaluating Pros and Cons of Euflexxa

Living with knee osteoarthritis can be a challenging journey, impacting mobility and quality of life. It is a chronic illness characterized by the gradual breakdown of cartilage in the knee. This vital cushioning tissue serves to absorb shock and allows smooth movement. As it erodes, individuals may experience osteoarthritis symptoms: knee pain, stiffness, and reduced range of motion. Activities that were once taken for granted, like climbing stairs or even walking, can become arduous tasks. Furthermore, knee osteoarthritis can lead to decreased independence. In some cases, it may even necessitate the use of assistive devices like canes or walkers.

As healthcare providers continue to explore diverse treatment options, hyaluronic acid injections like Euflexxa seem like a good choice. Check out this article to uncover its advantages and potential drawbacks.

Before we delve into the details, please note that the purchase of Euflexxa or any medical products at OGOMED requires certification as a medical professional. The use of these products should be undertaken by a specialist with appropriate education and level of expertise.

OGOMED is a leading supplier of medical solutions. Whether you’d like to buy Euflexxa or other brands, we have you covered. We offer a wide range of high-quality products at competitive prices.

General Information on Euflexxa

It is a type of intra-articular injection designed to alleviate the uncomfortable feeling in joints. There is a man-made version of hyaluronic acid, called hyaluronan, in the composition of Euflexxa. This acid is a natural component found in joint fluid, which provides lubrication and cushioning. When osteoarthritis appears, this natural fluid starts to thin out and can’t protect the knee as well.

Euflexxa increases fluid levels in the knee, potentially reducing pain and inflammation. The procedure involves the intra-articular administration of the filler directly into the affected cartilage. This method is considered minimally invasive. It provides an alternative for those who prefer non-surgical approaches to managing their knee osteoarthritis.

The Procedure of the Knee Cartilage Treatment

Treatment with Euflexxa includes a series of three weekly injections directly into the knee articulation. Each dose comes in a pre-filled glass syringe. Before the hyaluronic acid injections, your healthcare provider may need to remove extra fluid from around the knee. This helps decrease inflammation and ensures that the hyaluronan is not diluted when injected.

The injection is administered in the mid-kneecap region after the drainage process. While the initial needle prick may cause some discomfort, most people find that the injection itself doesn’t cause stinging or burning. However, it’s possible to experience short-term inflammation and pain in response to the hyaluronan.

For the first 48 hours after injection, it is recommended to avoid sports, strenuous exercise, running, heavy lifting, and prolonged standing. To experience the full benefits of the treatment takes about 5 weeks after completing the series. Typically, the effects last for at least three months and a maximum of up to 2 years.

orthopedic doctor hands make Euflexxa injection in knee

Benefits of Euflexxa Injections

Euflexxa treatment offers for individuals grappling with knee osteoarthritis the following potential benefits:

  1. Pain relief: Euflexxa helps alleviate cartilage pain, allowing you to move more comfortably and engage in your daily activities.
  2. Improved mobility: By restoring lubrication in the knee, Euflexxa may enhance mobility, making it easier to walk, climb stairs, and perform routine tasks.
  3. Minimally invasive: Unlike surgical options, Euflexxa injections are administered directly into the knee, requiring no major incisions or extensive recovery time.
  4. Delaying or avoiding surgery: Euflexxa can serve as an alternative for those seeking to postpone or avoid more invasive procedures like surgery or replacement.
  5. Long-lasting effects: Some individuals may experience significant pain reduction for an extended period, with reports of up to years.
  6. Potential to reduce inflammation: Euflexxa may help lessen swelling and redness, further contributing to pain reduction and improved function.
  7. Complementary to other treatments: This hyaluronic acid filler can be used in conjunction with other effective treatments, such as physical therapy or pain medication, to provide comprehensive care for osteoarthritis.
  8. Minimized side effects: While some individuals may experience mild pain or swelling at the injection site, serious side effects are rare.
  9. Non-systemic: Euflexxa is localized to the knee, minimizing the risk of systemic effects often associated with oral medications.
  10. Convenience: The injection process is relatively quick. Patients resume their normal activities shortly after the procedure.

These advantages collectively make Euflexxa injections a valuable option for those seeking effective relief from osteoarthritis.

Drawbacks of Euflexxa Treatments

While effective for many, Euflexxa treatments do come with some potential drawbacks:

  1. Temporary relief: Euflexxa injections may need to be given again and again over time to keep the effect working.
  2. Possible discomfort: Some individuals may experience mild pain, swelling, or redness, though this is temporary.
  3. Cost considerations: Depending on factors such as location, health condition, duration of the procedure, and health coverage, the cost of Euflexxa treatment may be a consideration for some individuals.
  4. Variable effectiveness: Response to Euflexxa can vary from person to person. While some may experience significant pain relief, others may not experience the same level of benefit.
  5. Risk of infection or allergic reactions: Although it’s rare cases, there is a small risk.
  6. Potential short-term inflammation: Some individuals may experience short-term redness or swelling at the injection site.
  7. Not suitable for severe cases: In advanced cases of osteoarthritis with significant joint space narrowing or severe symptoms, this hyaluronic acid filler may not provide as much relief as more invasive treatments like knee surgery.
  8. Post-treatment restrictions: Patients are advised to avoid strenuous activities, sports, and heavy lifting for the first 48 hours after the injections.
  9. Varied response: Scientists haven’t yet explained why some individuals experience complete pain relief, while others may not experience any change at all.

Before any medical procedure, discuss with the doctor your health condition and possible solutions.

PLEASE NOTE: Interested in exploring joint health solutions? Discover the differences between Euflexxa and Cortisone therapies in our article.

Common Side Effects after Euflexxa Injections

Adverse reactions after this procedure are generally mild and temporary. The most common side effect is mild knee pain or discomfort. Sometimes it may be swelling or redness. Usually, these reactions subside in a few days. In rare cases, it may occur in allergic reactions, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. They require immediate medical attention.

While the occurrence of serious side effects is rare, it’s recommended to consult with a healthcare provider about any concerns or potential risks associated with the treatment.

Alternative Ways to Treat Knee Joint Pain

There are several ways to treat osteoarthritis apart from Euflexxa injections. These include physical therapy, weight management, non-steroidal anti-inflammatory drugs (NSAIDs), heat and cold therapy, nutrition supplements, acupuncture, dietary changes, assistive devices, corticosteroid injections, lifestyle modifications, and surgical interventions.


Determining which way to treat osteoarthritis depends on the condition of your joints, overall health, and your preferences. Nevertheless, consultation with your doctor is crucial to ensure the most suitable solution for you.

Final Words

In weighing the advantages and disadvantages of Euflexxa injections for knee osteoarthritis, this treatment option holds significant potential for providing relief and improving quality of life. The benefits of Euflexxa, such as pain reduction, improved mobility, and its minimally invasive nature, make it an appealing choice. However, it’s vital to acknowledge the potential side effects and drawbacks, including the need for repeated injections and the possibility of temporary swelling, pain, or redness.

Overall, Euflexxa presents a valuable tool in the arsenal of treatments for knee joints. Consulting with healthcare providers is crucial in determining if Euflexxa aligns with individual needs, and has the potential for managing this chronic condition. We appreciate your visit to our blog. Keep an eye out for upcoming posts!